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Interleukin-15 Genotype, Random Writings

Well.. This is my first blog post to the new Exercise Science, LLC website. I will be posting more of my random writings from around the web on various subjects.

The first concerns the Interluekin-15 genotype and how it affects strength vs. muscle mass gains in response to a resistance program. This was originally posted in the bodybyscience.net discussion blog in response to a question.

Suresh,
“…is there any correlation as to how much strength gains(percentage gains) does it take to say gain a pound of muscle ie. have you observed any rough relationship that it takes roughly X percentage gains in strength to put a pound of muscle.”
Well.. This is my first blog post to the new Exercise Science, LLC website. I will be posting more of my random writings from around the web on various subjects.

The first concerns the Interluekin-15 genotype and how it affects strength vs. muscle mass gains in response to a resistance program. This was originally posted in the bodybyscience.net discussion blog in response to a question.

Suresh,
“…is there any correlation as to how much strength gains(percentage gains) does it take to say gain a pound of muscle ie. have you observed any rough relationship that it takes roughly X percentage gains in strength to put a pound of muscle.”

I’m not aware of any evidence and would be highly suspect of any evidence indicating such. Genetics research indicates that the amount of muscle mass gained per unit strength increase is highly variable between individuals, depending upon genotype. This was touched upon in Body by Science, and was discussed thoroughly in my Genetic Variability lecture at the 2006 High Intensity training seminar.

Moreover, depending upon interleukin-15 genotype, the subjects adding the most muscle mass gained the least amount of strength. Conversely, the subjects that gained the most strength gained the least amount of muscle mass. Here is a quote:

“Hypertrophy has been considered the ideal response to resistance training and cellular studies of muscle growth, but muscle quality has been examined recently to reflect a measure of mass to performance efficiency. If neurological and biochemical adaptations are not sufficient to respond to the overload stimulus, hypertrophy may be a compensating adaptation.”

See the following:

Journal of Applied Physiology 97:2214-2219, 2004. Steven E. Riechman, G. Balasekaran, Stephen M. Roth and Robert E. Ferrell Association of interleukin-15 protein and interleukin-15 receptor genetic variation with resistance exercise training responses





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